Blaise Aguera y Arcas, Partner architect, MSN and Microsoft Visual Earth Techies have long sought to display huge files in high resolution without crashing a computer.

Chris Ferguson has claimed some $7.3 million in winnings. But his biggest bet was starting Full Tilt Poker with 12 pros who join in online games instead of the usual one or two. Full Tilt is one of the fastest-growing poker sites in the world.

Evan Williams, CEO, Twitter @ev Site getting more buzz than F-book. Yearly traffic up 1,200%. Estimated worth = $500 million+.

Henrik Werdelin, Chief creative officer, Joost Inspired by how people move in the real world, Werdelin has led the transformation of Joost into a "learning" site that tracks how you watch and what you share with friends, and customizes itself by, say, automatically moving up your fave features.

Michele Ganeless, President, Comedy Central First came South Park, then The Daily Show and its Colbert spin-off.

Reed Hastings, Chief Executive Officer, Netflix Reed Hastings could have stuck with his first breakthrough idea--Netflix recently mailed its 2-billionth DVD.

Scott Schuman, Blogger Scott Schuman started his fashion blog, The Sartorialist, to "share photos of everyday people I thought looked great."